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CFL1 Rabbit pAb

Anti-CFL1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217295

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217295
Product Name:   Anti-CFL1 Rabbit Polyclonal Antibody
Synonyms:   CFL
UNIPROT ID:   P23528 (Gene Accession – BC011005 )
Background:    The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Immunogen:    Fusion protein of human CFL1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human gasrtic cancer tissue using 217295(CFL1 Antibody) at a dilution of 1/30(Cytoplasm).
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