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CFL2 Rabbit pAb

Anti-CFL2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221758

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221758
Product Name:   Anti-CFL2 Rabbit Polyclonal Antibody
Synonyms:   NEM7
UNIPROT ID:   Q9Y281 (Gene Accession – NP_068733 )
Background:    This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human CFL2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221758(CFL2 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221758(Anti-CFL2 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 221758(Anti-CFL2 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D263489(Anti-CFL2 Antibody) at dilution 1/20.
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