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CFTR Rabbit pAb

Anti-CFTR Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219694

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219694
Product Name:   Anti-CFTR Rabbit Polyclonal Antibody
Synonyms:   CF, MRP7, ABC35, ABCC7, CFTR/MRP, TNR-CFTR, dJ760C5.1
UNIPROT ID:   P13569 (Gene Accession – NP_000483 )
Background:    This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene.
Immunogen:    Synthetic peptide of human CFTR
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 500-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219694(CFTR Antibody) at a dilution of 1/10(Cytoplasm, Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 219694(Anti-CFTR Antibody) at dilution 1/10.
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