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CHRM5 Rabbit pAb

Anti-CHRM5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221188

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221188
Product Name:   Anti-CHRM5 Rabbit Polyclonal Antibody
Synonyms:   HM5
UNIPROT ID:   P08912 (Gene Accession – NP_036257 )
Background:    The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels.
Immunogen:    Synthetic peptide of human CHRM5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221188(CHRM5 Antibody) at a dilution of 1/25(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221188(Anti-CHRM5 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 221188(Anti-CHRM5 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with synthetic peptide and then with D262682(Anti-CHRM5 Antibody) at dilution 1/25.
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