NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N225576 | ||
Product Name: Anti-CKII alpha Rabbit pAb | ||
Synonyms: CSNK2A1; CK2A1; Casein kinase II subunit alpha; CK II alpha | ||
UNIPROT ID: P68400 | ||
Background: Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. | ||
Immunogen: A synthesized peptide derived from human CKII alpha | ||
Applications: WB,IHC-P,FC | ||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Polyclonal | ||
Clone ID: – | ||
MW: Calculated MW: 45 kDa; Observed MW: 45 kDa | ||
Isotype: IgG | ||
Purification: Affinity Chromatography | ||
Species Reactivity: Human,Mouse,Rat | ||
Conjugation: Unconjugated | ||
Modification: Unmodified | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
Research Areas: EpigeneticsyyyyyHistone phosphorylation | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
|