Email: info@neweastbio.com   |  Call: 6109452007

CLCN7 Rabbit pAb

Anti-CLCN7 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218507

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218507
Product Name:   Anti-CLCN7 Rabbit Polyclonal Antibody
Synonyms:   HOD; CLC7; CLC-7; OPTA2; OPTB4; PPP1R63
UNIPROT ID:   P51798 (Gene Accession – BC012737 )
Background:    The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
Immunogen:    Fusion protein of human CLCN7
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-300;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218507(CLCN7 Antibody) at a dilution of 1/100(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218507(Anti-CLCN7 Antibody) at dilution 1/100.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: HepG2, A549, LOVO cell lysates;
Primary antibody: 218507(CLCN7 Antibody) at dilution 1/500;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 2 minutes
          Publications