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CLEC7A Rabbit pAb

Anti-CLEC7A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216404

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216404
Product Name:   Anti-CLEC7A Rabbit Polyclonal Antibody
Synonyms:   BGR; CD369; CANDF4; SCARE2; DECTIN1; CLECSF12
UNIPROT ID:   Q9BXN2 (Gene Accession – BC013385 )
Background:    This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
Immunogen:    Fusion protein of human CLEC7A
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 216404(CLEC7A Antibody) at a dilution of 1/80(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 216404(Anti-CLEC7A Antibody) at dilution 1/80.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 216404(Anti-CLEC7A Antibody) at a dilution of 1/80.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with fusion protein and then with D220382(Anti-CLEC7A Antibody) at dilution 1/80.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: 231 cell lysate;
Primary antibody: 216404(CLEC7A Antibody) at dilution 1/250;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 90 seconds
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