NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S218512 | ||
Product Name: Anti-CLPTM1 Rabbit Polyclonal Antibody | ||
Synonyms: | ||
UNIPROT ID: O96005 (Gene Accession – BC012359 ) | ||
Background: Clefts of the oral-facial region usually occur in early fetal development and can affect the lip, the soft palate (the soft tissue in the back of the mouth) and the hard palate (the roof of the mouth). Cleft lip (with or without cleft palate) is a genetically complex birth defect that occurs in approximately one in every 750-1,000 live births. This is one of the most common birth defects and is multifactorial, with both genetic and environmental causes. Cleft lip- and palate-associated transmembrane protein 1 (CLPTM1) belongs to a family of cleft lip and palate transmembrane proteins. This family also contains cisplatin resistance-related protein (CRR9), which is involved in CDDP-induced apoptosis. The CLPTM1 protein shows strong homology to two Caenorhabditis elegans genes. | ||
Immunogen: Fusion protein of human CLPTM1 | ||
Applications: ELISA, IHC | ||
Recommended Dilutions: IHC: 20-100; ELISA: 5000-10000 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Polyclonal | ||
Isotype: Immunogen-specific rabbit IgG | ||
Purification: Antigen affinity purification | ||
Species Reactivity: Human, Mouse | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||
Research Areas: Cell Biology | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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