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CMKLR1 Rabbit pAb

Anti-CMKLR1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225435

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225435
Product Name:   Anti-CMKLR1 Rabbit pAb
Synonyms:   DEZ; RVER1; ChemR23; CHEMERINR
UNIPROT ID:   Q99788
Background:    Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
Immunogen:    The antiserum was produced against synthesized peptide derived from human CMKLR1. AA range:221-270
Applications:    WB,IHC-F,IHC-P,ICC/IF,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 42 kDa; Observed MW: 42 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of CMKLR1 in 293T lysates using ChemR23 antibody.

Western blot analysis of CMKLR1 in various lysates using CMKLR1 antibody.

Western blot analysis of CMKLR1 in COLO205 lysates using ChemR23 antibody.

Western blot analysis of CMKLR1 in 293T lysates using CMKLR1 antibody.
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