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CNGB1 Rabbit pAb

Anti-CNGB1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225440

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225440
Product Name:   Anti-CNGB1 Rabbit pAb
Synonyms:   CNG4; GAR1; GARP; RP45; CNCG2; CNCG4; GARP2; RCNC2; RCNCb; CNCG3L; CNGB1B; RCNCbeta
UNIPROT ID:   Q14028
Background:    Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP.Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties: it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor ‘dark noise’ and allowing these sensory cells to operate at the single photon detection limit.
Immunogen:    The antiserum was produced against synthesized peptide derived from human CNGB1. AA range:571-620
Applications:    WB,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 140 kDa; Observed MW: 102 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of CNGB1 in NIH/3T3 and A549 lysates using CNGB1 antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of CNGB1 in various lysates using CNGB1 antibody.

Western blot analysis of CNGB1 in 3T3 lysates using CNG1???? antibody.
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