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CNOT2 Rabbit pAb

Anti-CNOT2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218519

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218519
Product Name:   Anti-CNOT2 Rabbit Polyclonal Antibody
Synonyms:   NOT2; CDC36; NOT2H; HSPC131
UNIPROT ID:   Q9NZN8 (Gene Accession – BC002597 )
Background:    This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene.
Immunogen:    Fusion protein of human CNOT2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218519(CNOT2 Antibody) at a dilution of 1/20(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218519(Anti-CNOT2 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 218519(Anti-CNOT2 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D224604(Anti-CNOT2 Antibody) at dilution 1/20.
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