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CNR1 Rabbit pAb

Anti-CNR1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219708

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219708
Product Name:   Anti-CNR1 Rabbit Polyclonal Antibody
Synonyms:   CB1; CNR; CB-R; CB1A; CB1R; CANN6; CB1K5
UNIPROT ID:   P21554 (Gene Accession – NP_001153698 )
Background:    This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
Immunogen:    Synthetic peptide of human CNR1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Neuroscience, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219708(CNR1 Antibody) at a dilution of 1/20(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 219708(Anti-CNR1 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 219708(Anti-CNR1 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D260190(Anti-CNR1 Antibody) at dilution 1/20.
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