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COL1A2 Rabbit pAb

Anti-COL1A2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216343

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216343
Product Name:   Anti-COL1A2 Rabbit Polyclonal Antibody
Synonyms:   OI4; EDSCV; EDSARTH2
UNIPROT ID:   P08123 (Gene Accession – BC042586 )
Background:    This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Immunogen:    Fusion protein of human COL1A2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 216343(COL1A2 Antibody) at a dilution of 1/55(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 216343(Anti-COL1A2 Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 216343(Anti-COL1A2 Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D220244(Anti-COL1A2 Antibody) at dilution 1/55.
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