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CRP Rabbit pAb

Anti-CRP Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216446

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216446
Product Name:   Anti-CRP Rabbit Polyclonal Antibody
Synonyms:   PTX1
UNIPROT ID:   P02741 (Gene Accession – BC020766 )
Background:    The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection.
Immunogen:    Fusion protein of human CRP
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using 216446(CRP Antibody) at a dilution of 1/55(Cytoplasm).


Immunohistochemistry analysis of paraffin-embedded Human cervical cancer tissue using 216446(Anti-CRP Antibody) at a dilution of 1/55.


Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse liver tissue, HL60 cell lysates;
Primary antibody: 216446(CRP Antibody) at dilution 1/400;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 15 seconds
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