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CSF1R Rabbit pAb

Anti-CSF1R Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213656

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213656
Product Name:   Anti-CSF1R Rabbit Polyclonal Antibody
Synonyms:   FMS, CSFR, FIM2, HDLS, C-FMS, CD115, CSF-1R, M-CSF-R
UNIPROT ID:   P07333 (Gene Accession – NP_005202 )
Background:    The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.
Immunogen:    Synthetic peptide of human CSF1R
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 213656(CSF1R Antibody) at a dilution of 1/45(cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 213656(Anti-CSF1R Antibody) at dilution 1/45.
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