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CSNK2A2 Rabbit pAb

Anti-CSNK2A2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218504

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218504
Product Name:   Anti-CSNK2A2 Rabbit Polyclonal Antibody
Synonyms:   CK2A2; CSNK2A1; CK2alpha’
UNIPROT ID:   P19784 (Gene Accession – BC008812 )
Background:    This gene encodes the alpha’, or alpha 2, catalytic subunit of the protein kinase enzyme, casein kinase 2 (CK2). Casein kinase 2 is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha’, and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11.
Immunogen:    Fusion protein of human CSNK2A2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-300;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218504(CSNK2A2 Antibody) at a dilution of 1/150(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218504(Anti-CSNK2A2 Antibody) at dilution 1/150.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 218504(Anti-CSNK2A2 Antibody) at a dilution of 1/150.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with fusion protein and then with D224570(Anti-CSNK2A2 Antibody) at dilution 1/150.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: K562 and Jurkat cell lysates;
Primary antibody: 218504(CSNK2A2 Antibody) at dilution 1/900;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
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