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CTLA4 Rabbit pAb

Anti-CTLA4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219723

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219723
Product Name:   Anti-CTLA4 Rabbit Polyclonal Antibody
Synonyms:   CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3
UNIPROT ID:   P16410 (Gene Accession – NP_005205 )
Background:    This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Immunogen:    Synthetic peptide of human CTLA4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human prostate cancer tissue using 219723(CTLA4 Antibody) at a dilution of 1/50(Cytoplasm and Cell membrane).
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