Email: info@neweastbio.com   |  Call: 6109452007

CTSB Rabbit pAb

Anti-CTSB Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216395

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216395
Product Name:   Anti-CTSB Rabbit Polyclonal Antibody
Synonyms:   APPS, CPSB
UNIPROT ID:   P07858 (Gene Accession – BC010240 )
Background:    The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
Immunogen:    Fusion protein of human CTSB
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216395(CTSB Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216395(Anti-CTSB Antibody) at dilution 1/35.
          Publications