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CTSK Rabbit pAb

Anti-CTSK Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221183

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221183
Product Name:   Anti-CTSK Rabbit Polyclonal Antibody
Synonyms:   CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2
UNIPROT ID:   P43235 (Gene Accession – NP_000387 )
Background:    The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
Immunogen:    Synthetic peptide of human CTSK
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cell Biology, Neuroscience, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221183(CTSK Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221183(Anti-CTSK Antibody) at dilution 1/20.
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