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CUL4B Rabbit pAb

Anti-CUL4B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220485

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220485
Product Name:   Anti-CUL4B Rabbit Polyclonal Antibody
Synonyms:   SFM2; MRXSC; MRXHF2; MRXS15
UNIPROT ID:   Q13620 (Gene Accession – NP_003579 )
Background:    This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human CUL4B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220485(CUL4B Antibody) at a dilution of 1/50(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220485(Anti-CUL4B Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 220485(Anti-CUL4B Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D261596(Anti-CUL4B Antibody) at dilution 1/50.
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