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CUTA Rabbit pAb

Anti-CUTA Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218558

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218558
Product Name:   Anti-CUTA Rabbit Polyclonal Antibody
Synonyms:   ACHAP; C6orf82
UNIPROT ID:   O60888 (Gene Accession – BC005890 )
Background:    CUTA, also known as ACHAP (acetylcholinesterase-associated protein), is the 179 amino acid mammalian homolog of the cutA E. coli protein and is ubiquitously expressed, particularly in brain tissue. Existing as multiple alternatively spliced isoforms, CUTA functions as a homotrimer that is thought to act as a component of an acetylcholinesterase (AChE)-attached comple,x suggesting an involvement in AChE regulation. The gene encoding CUTA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson’s disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Immunogen:    Fusion protein of human CUTA
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 218558(CUTA Antibody) at a dilution of 1/40(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the fusion protein and then with 218558(Anti-CUTA Antibody) at dilution 1/40.
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