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Cyclooxygenase 2 Rabbit mAb

Anti-Cyclooxygenase 2 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262058

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262058
Product Name:   Anti-Cyclooxygenase 2 Rabbit Monoclonal Antibody
Synonyms:   COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
UNIPROT ID:   P35354
Background:    Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Immunogen:    A synthetic peptide of human COX2
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R04-3I1
MW:    Calculated MW: 69 kDa; Observed MW: 69 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using COX2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of COX2/cyclooxygenase2 in rat Brain lysates using Cyclooxygenase 2 antibody.
          Publications