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Cyclooxygenase 2 Rabbit mAb

Anti-Cyclooxygenase 2 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262059

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262059
Product Name:   Anti-Cyclooxygenase 2 Rabbit Monoclonal Antibody
Synonyms:   COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
UNIPROT ID:   P35354
Background:    Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Immunogen:    Recombinant protein of human COX2/Cyclooxygenase 2
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R05-2I3
MW:    Calculated MW: 69 kDa; Observed MW: 74 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of COX2/Cyclooxygenase 2 in 3T3 lysates using COX2/Cyclooxygenase 2 antibody.

Western blot analysis of COX2/Cyclooxygenase 2 in A549 lysates using Cyclooxygenase 2 antibody.
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