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CYP19A1 Rabbit pAb

Anti-CYP19A1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219661

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219661
Product Name:   Anti-CYP19A1 Rabbit Polyclonal Antibody
Synonyms:   ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
UNIPROT ID:   P11511 (Gene Accession – NP_000094 )
Background:    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity, the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
Immunogen:    Synthetic peptide of human CYP19A1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer, Metabolism, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 219661(CYP19A1 Antibody) at a dilution of 1/35(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 219661(Anti-CYP19A1 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 219661(Anti-CYP19A1 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D260102(Anti-CYP19A1 Antibody) at dilution 1/35.
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