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CYP24A1 Rabbit pAb

Anti-CYP24A1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222354

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222354
Product Name:   Anti-CYP24A1 Rabbit Polyclonal Antibody
Synonyms:   CP24; HCAI; CYP24; HCINF1; P450-CC24
UNIPROT ID:   Q07973 (Gene Accession – NP_000773 )
Background:    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human CYP24A1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cardiovascular, Metabolism, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 222354(CYP24A1 Antibody) at a dilution of 1/60(Mitochondrion).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 222354(Anti-CYP24A1 Antibody) at dilution 1/60.
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