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CYP2C9 Rabbit pAb

Anti-CYP2C9 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217319

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217319
Product Name:   Anti-CYP2C9 Rabbit Polyclonal Antibody
Synonyms:   CPC9; CYP2C; CYP2C10; CYPIIC9; P450IIC9
UNIPROT ID:   P11712 (Gene Accession – BC020754 )
Background:    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
Immunogen:    Fusion protein of human CYP2C9
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217319(CYP2C9 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217319(Anti-CYP2C9 Antibody) at dilution 1/50.
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