NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N261527 |
Product Name: Anti-Cytokeratin 18 Mouse Monoclonal Antibody |
Synonyms: Cell proliferation inducing gene 46 protein; Cell proliferation inducing protein 46; Cell proliferation-inducing gene 46 protein; CK 18; CK-18; CK18; CYK 18; CYK18; Cytokeratin 18; Cytokeratin endo B; Cytokeratin-18; K 18; K18; K1C18_HUMAN; Keratin 18; Keratin D; keratin; type I cytoskeletal 18; Keratin-18; KRT18. |
UNIPROT ID: P05783 |
Background: K18 a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 18 and its filament partner keratin 8 are perhaps the most commonly found members of the intermediate filament gene family. |
Immunogen: Purified recombinant human Keratin 18 protein fragments expressed in E.coli. |
Applications: WB,ICC/IF |
Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 |
Host Species: Mouse |
Clonality: Mouse Monoclonal |
Clone ID: 2B5-B6-F7 |
MW: Calculated MW: 48 kDa; Observed MW: 48 kDa |
Isotype: IgG2a |
Purification: Affinity Purified |
Species Reactivity: Human,Monkey,Mouse |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Tags & Cell Markers |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of Keratin 18 in COS7, 3T3 and Hela lysates using Keratin 18 antibody. |