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DAGLB Rabbit pAb

Anti-DAGLB Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221877

   Size:   100 μl

In Stock

            Product Description          
Cat.#:   S221877
Product Name:   Anti-DAGLB Rabbit Polyclonal Antibody
Synonyms:   KCCR13L; DAGLBETA
UNIPROT ID:   Q8NCG7 (Gene Accession – NP_631918 )
Background:    Members of the AB hydrolase superfamily have diverse catalytic functions and play a crucial role in the metabolism of lipids. DAGL? (diacylglycerol lipase beta), also known as KCCR13L, is a 672 amino acid multi-pass membrane protein that belongs to the AB hydrolase superfamily. DAGL? uses calcium as a cofactor to catalyze the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), a reaction that is required for axonal growth and for retrograde synaptic signaling at mature synapses. DAGL? functions at an optimal pH of 7 and its activity is inhibited by p-hydroxy-mercuri-benzoate and HgCl2, but not PMSF. There are three isoforms of DAGL? that are produced as a result of alternative splicing events.
Immunogen:    Synthetic peptide of human DAGLB
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221877(DAGLB Antibody) at a dilution of 1/20(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221877(Anti-DAGLB Antibody) at dilution 1/20.
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