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DAPK2 Rabbit mAb

Anti-DAPK2 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262113

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262113
Product Name:   Anti-DAPK2 Rabbit Monoclonal Antibody
Synonyms:   DAPK2; Death-associated protein kinase 2; DAP kinase 2; DAP-kinase-related protein 1; DRP-1
UNIPROT ID:   Q9UIK4
Background:    Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421).
Immunogen:    A synthetic peptide of human DAPK2
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R09-8F2
MW:    Calculated MW: 43 kDa; Observed MW: 43 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of DAPK2 in rat spleen lysates using DAPK2 antibody.
          Publications