NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S217343 | ||||
Product Name: Anti-DCBLD2 Rabbit Polyclonal Antibody | ||||
Synonyms: ESDN; CLCP1 | ||||
UNIPROT ID: Q96PD2 (Gene Accession – BC029658 ) | ||||
Background: CLCP1 (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1), also known as DCBLD2 (discoidin, CUB and LCCL domain containing 2) or ESDN, is a 775 amino acid single-pass type I membrane protein that contains one CUB domain, one LCCL domain and one F5/8 type C domain. Expressed at high levels in heart, testis and skeletal muscle, CLCP1 is thought to regulate vascular smooth muscle cell (VSMC) proliferation and remodeling and may be involved in the transformation and metastasis of various cancers, such as metastatic lung cancer and gastric carcinoma. | ||||
Immunogen: Fusion protein of human DCBLD2 | ||||
Applications: ELISA, IHC | ||||
Recommended Dilutions: IHC: 100-300; ELISA: 2000-10000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human, Mouse, Rat | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Signal Transduction, Cardiovascular | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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