Email: info@neweastbio.com   |  Call: 6109452007

DCX Rabbit pAb

Anti-DCX Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221268

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221268
Product Name:   Anti-DCX Rabbit Polyclonal Antibody
Synonyms:   DC; DBCN; LISX; SCLH; XLIS
UNIPROT ID:   O43602 (Gene Accession – NP_000546 )
Background:    This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing corte,x cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex.
Immunogen:    Synthetic peptide of human DCX
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 221268(DCX Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 221268(Anti-DCX Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 221268(Anti-DCX Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with synthetic peptide and then with D262787(Anti-DCX Antibody) at dilution 1/35.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: 293T, K562 and Raji cell;
Primary antibody: 221268(DCX Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 15 seconds
          Publications