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DDAH1 Rabbit pAb

Anti-DDAH1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220325

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220325
Product Name:   Anti-DDAH1 Rabbit Polyclonal Antibody
Synonyms:   DDAH
UNIPROT ID:   O94760 (Gene Accession – NP_001127917 )
Background:    This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
Immunogen:    Synthetic peptide of human DDAH1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220325(DDAH1 Antibody) at a dilution of 1/55(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220325(Anti-DDAH1 Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220325(Anti-DDAH1 Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D261354(Anti-DDAH1 Antibody) at dilution 1/55.
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