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DDI1 Rabbit pAb

Anti-DDI1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218583

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218583
Product Name:   Anti-DDI1 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   Q8WTU0 (Gene Accession – BC022017 )
Background:    DDI1 and DDI2 are ubiquitin receptor homologs of the Saccharomyces cerevisiae ddi1 protein, which is involved in regulation of the cell cycle and the late secretory pathway. DDI1 is a 396 amino acid protein that contains one ubiquitin-like domain. The gene encoding DDI1 maps to human chromosome 11, which makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and ? thalassemia are caused by HBB gene mutations. Wilms’ tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene.
Immunogen:    Fusion protein of human DDI1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 218583(DDI1 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 218583(Anti-DDI1 Antibody) at dilution 1/40.
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