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DEFA1 Rabbit pAb

Anti-DEFA1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219739

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219739
Product Name:   Anti-DEFA1 Rabbit Polyclonal Antibody
Synonyms:   HP1, MRS, DEF1, HP-1, DEFA2, HNP-1
UNIPROT ID:   P59665 (Gene Accession – NP_004075 )
Background:    Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
Immunogen:    Synthetic peptide of human DEFA1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-May; ELISA: 500-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219739(DEFA1 Antibody) at a dilution of 1/10(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 219739(Anti-DEFA1 Antibody) at dilution 1/10.
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