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DEFA5 Rabbit pAb

Anti-DEFA5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220367

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220367
Product Name:   Anti-DEFA5 Rabbit Polyclonal Antibody
Synonyms:   DEF5; HD-5
UNIPROT ID:   Q01523 (Gene Accession – NP_066290 )
Background:    Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.
Immunogen:    Synthetic peptide of human DEFA5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 15-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 220367(DEFA5 Antibody) at a dilution of 1/15(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the synthetic peptide and then with 220367(Anti-DEFA5 Antibody) at dilution 1/15.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220367(Anti-DEFA5 Antibody) at a dilution of 1/15.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D261435(Anti-DEFA5 Antibody) at dilution 1/15.
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