NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S220509 | ||||
Product Name: Anti-DIRAS1 Rabbit Polyclonal Antibody | ||||
Synonyms: RIG; GBTS1; Di-Ras1 | ||||
UNIPROT ID: O95057 (Gene Accession – NP_660156 ) | ||||
Background: DIRAS1 (DIRAS family, GTP-binding Ras-like 1), also known as distinct subgroup of the Ras family member 1, RIG (Ras-related inhibitor of cell growth), small GTP-binding tumor suppressor 1 or GBTS1, is a 198 amino acid cell membrane protein expressed at high levels in brain and heart. DIRAS1 displays low GTPase activity and is encoded by a gene that maps to human chromosome 19p13.3. | ||||
Immunogen: Synthetic peptide of human DIRAS1 | ||||
Applications: ELISA, IHC | ||||
Recommended Dilutions: IHC: 50-200; ELISA: 1000-5000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Signal Transduction | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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