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DNA2 Rabbit pAb

Anti-DNA2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219461

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219461
Product Name:   Anti-DNA2 Rabbit Polyclonal Antibody
Synonyms:   DNA2L; hDNA2
UNIPROT ID:   P51530 (Gene Accession – BC111740 )
Background:    This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene.
Immunogen:    Fusion protein of human DNA2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 219461(DNA2 Antibody) at a dilution of 1/40(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 219461(Anti-DNA2 Antibody) at dilution 1/40.
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