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DNMT1 Rabbit pAb

Anti-DNMT1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219746

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219746
Product Name:   Anti-DNMT1 Rabbit Polyclonal Antibody
Synonyms:   AIM, DNMT, MCMT, CXXC9, HSN1E
UNIPROT ID:   P26358 (Gene Accession – NP_001370 )
Background:    DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human DNMT1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 500-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 219746(DNMT1 Antibody) at a dilution of 1/12(Cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 219746(Anti-DNMT1 Antibody) at dilution 1/12.
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