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DOHH Rabbit mAb

Anti-DOHH Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262147

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262147
Product Name:   Anti-DOHH Rabbit Monoclonal Antibody
Synonyms:   HLRC1; hDOHH
UNIPROT ID:   Q9BU89
Background:    Catalyzes the hydroxylation of the N6-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine (PubMed:16533814, PubMed:16371467, PubMed:19706422). Hypusination is unique to mature eIF-5A factor and is essential for its function .
Immunogen:    A synthetic peptide of human DOHH
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R04-4I8
MW:    Calculated MW: 33 kDa; Observed MW: 33 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of DOHH in K562, Hela lysates using DOHH antibody.
          Publications