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DPPA4 Rabbit pAb

Anti-DPPA4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221327

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221327
Product Name:   Anti-DPPA4 Rabbit Polyclonal Antibody
Synonyms:   2410091M23Rik
UNIPROT ID:   Q7L190 (Gene Accession – NP_060659 )
Background:    This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human DPPA4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Stem Cells, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 221327(DPPA4 Antibody) at a dilution of 1/55(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 221327(Anti-DPPA4 Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 221327(Anti-DPPA4 Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D262869(Anti-DPPA4 Antibody) at dilution 1/55.
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