Email: info@neweastbio.com   |  Call: 6109452007

DR1 Rabbit pAb

Anti-DR1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215610

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215610
Product Name:   Anti-DR1 Rabbit Polyclonal Antibody
Synonyms:   NC2; NC2B; NC2-BETA
UNIPROT ID:   Q01658 (Gene Accession – NP_001929 )
Background:    This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
Immunogen:    Synthetic peptide of human DR1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 215610(DR1 Antibody) at a dilution of 1/25(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 215610(Anti-DR1 Antibody) at dilution 1/25.
          Publications