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DSC2 Rabbit pAb

Anti-DSC2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220505

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220505
Product Name:   Anti-DSC2 Rabbit Polyclonal Antibody
Synonyms:   DG2; DSC3; CDHF2; ARVD11; DGII/III
UNIPROT ID:   Q02487 (Gene Accession – NP_077740 )
Background:    The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.
Immunogen:    Synthetic peptide of human DSC2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 220505(DSC2 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the synthetic peptide and then with 220505(Anti-DSC2 Antibody) at dilution 1/25.
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