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DSG2 Rabbit pAb

Anti-DSG2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217359

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217359
Product Name:   Anti-DSG2 Rabbit Polyclonal Antibody
Synonyms:   HDGC; CDHF5; ARVC10; ARVD10; CMD1BB
UNIPROT ID:   Q14126 (Gene Accession – BC099655 )
Background:    Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.
Immunogen:    Fusion protein of human DSG2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217359(DSG2 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217359(Anti-DSG2 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 217359(Anti-DSG2 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D222230(Anti-DSG2 Antibody) at dilution 1/70.
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