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DUSP10 Rabbit pAb

Anti-DUSP10 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216502

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216502
Product Name:   Anti-DUSP10 Rabbit Polyclonal Antibody
Synonyms:   MKP5; MKP-5
UNIPROT ID:   Q9Y6W6 (Gene Accession – BC031405 )
Background:    Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Immunogen:    Fusion protein of human DUSP10
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 216502(DUSP10 Antibody) at a dilution of 1/120(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 216502(Anti-DUSP10 Antibody) at dilution 1/120.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 216502(Anti-DUSP10 Antibody) at a dilution of 1/120.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D220609(Anti-DUSP10 Antibody) at dilution 1/120.
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