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DVL1 Rabbit pAb

Anti-DVL1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221219

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221219
Product Name:   Anti-DVL1 Rabbit Polyclonal Antibody
Synonyms:   DVL; DRS2; DVL1L1; DVL1P1
UNIPROT ID:   O14640 (Gene Accession – NP_004412 )
Background:    DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Immunogen:    Synthetic peptide of human DVL1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 221219(DVL1 Antibody) at a dilution of 1/20(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 221219(Anti-DVL1 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 221219(Anti-DVL1 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D262725(Anti-DVL1 Antibody) at dilution 1/20.
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