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DYNC1LI2 Rabbit pAb

Anti-DYNC1LI2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221927

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221927
Product Name:   Anti-DYNC1LI2 Rabbit Polyclonal Antibody
Synonyms:   LIC2; DNCLI2
UNIPROT ID:   O43237 (Gene Accession – NP_006132 )
Background:    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
Immunogen:    Synthetic peptide of human DYNC1LI2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 20-100;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221927(DYNC1LI2 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221927(Anti-DYNC1LI2 Antibody) at dilution 1/25.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-5: Hela and PC-3 cell, Mouse brain tissue, SKOV3 cell, Human fetal brain tissue lysates;
Primary antibody: 221927(DYNC1LI2 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 3 minutes
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