Email: info@neweastbio.com   |  Call: 6109452007

ECM1 Rabbit pAb

Anti-ECM1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221229

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221229
Product Name:   Anti-ECM1 Rabbit Polyclonal Antibody
Synonyms:   URBWD
UNIPROT ID:   Q16610 (Gene Accession – NP_073155 )
Background:    This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.
Immunogen:    Synthetic peptide of human ECM1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-50;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 221229(ECM1 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 221229(Anti-ECM1 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 221229(Anti-ECM1 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with synthetic peptide and then with D262737(Anti-ECM1 Antibody) at dilution 1/25.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: LOVO and LO2 cell lysates;
Primary antibody: 221229(ECM1 Antibody) at dilution 1/650;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
          Publications