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EDARADD Rabbit pAb

Anti-EDARADD Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S211884

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S211884
Product Name:   Anti-EDARADD Rabbit Polyclonal Antibody
Synonyms:   ED3; EDA3; ECTD11A; ECTD11B
UNIPROT ID:   Q8WWZ3 (Gene Accession – BC128082 )
Background:    This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Immunogen:    Full length fusion protein
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 35-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 211884(EDARADD Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 211884(Anti-EDARADD Antibody) at dilution 1/50.
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