Email: info@neweastbio.com   |  Call: 6109452007

EDEM1 Rabbit pAb

Anti-EDEM1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215696

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215696
Product Name:   Anti-EDEM1 Rabbit Polyclonal Antibody
Synonyms:   EDEM
UNIPROT ID:   Q92611 (Gene Accession – NP_055489 )
Background:    Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
Immunogen:    Synthetic peptide of human EDEM1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 215696(EDEM1 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 215696(Anti-EDEM1 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 215696(Anti-EDEM1 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D163755(Anti-EDEM1 Antibody) at dilution 1/20.
          Publications