Email: info@neweastbio.com   |  Call: 6109452007

EDNRB Rabbit pAb

Anti-EDNRB Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219756

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219756
Product Name:   Anti-EDNRB Rabbit Polyclonal Antibody
Synonyms:   ETB; ET-B; ETB1; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2
UNIPROT ID:   P24530 (Gene Accession – NP_003982 )
Background:    The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Immunogen:    Synthetic peptide of human EDNRB
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 219756(EDNRB Antibody) at a dilution of 1/55(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 219756(Anti-EDNRB Antibody) at dilution 1/55.
          Publications